Laboratory of Mucosal ImmunologyIn the Department of Medicine and Pediatrics
Director: Dr. Martin Kagnoff

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2005-2001 2000-2001 1999-1997 1996-1994 1993-1990 1989-1980 1979-1970


  • Eckmann L, Kagnoff MF.
    Intestinal mucosal responses to microbial infection.
    Springer Semin Immunopathol. 2005 Jun 1;
    PMID: 15928914
  • Kagnoff MF.
    Overview and pathogenesis of celiac disease. Gastroenterology. 2005 Apr;128(4 Pt 2):S10-8. No abstract available.
    PMID: 15825116
  • Iimura M, Gallo RL, Hase K, Miyamoto Y, Eckmann L, Kagnoff MF.
    Cathelicidin Mediates Innate Intestinal Defense against Colonization with Epithelial Adherent Bacterial Pathogens. J Immunol. 2005 Apr 15;174(8):4901-7.
    PMID: 15814717
  • Maeda S, Hsu LC, Liu H, Bankston LA, Iimura M, Kagnoff MF, Eckmann L, Karin M.
    Nod2 mutation in Crohn's disease potentiates NF-kappaB activity and IL-1beta processing.
    Science. 2005 Feb 4;307(5710):734-8.
    PMID: 15692052
  • Yang CC, Ogawa H, Dwinell MB, McCole DF, Eckmann L, Kagnoff MF.
    Chemokine receptor CCR6 transduces signals that activate p130Cas and alter cAMP-stimulated ion transport in human intestinal epithelial cells.
    Am J Physiol Cell Physiol.2005 Feb;288(2):C321-8. Epub 2004 Oct 13.
    PMID: 15483227
  • Greten FR, Eckmann L, Greten TF, Park JM, Li ZW, Egan LJ, Kagnoff MF, Karin M.
    IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer.
    Cell. 2004 Aug 6;118(3):285-96.
    PMID: 15294155
  • Ogawa H, Iimura M, Eckmann L, Kagnoff MF.
    Regulated production of the chemokine CCL28 in human colon epithelium.
    Am J Physiol Gastrointest Liver Physiol. 2004 Jul 8 [Epub ahead of print]
    PMID: 15246961
  • Maaser C, Egan LJ, Birkenbach MP, Eckmann L, Kagnoff MF.
    Expression of Epstein-Barr virus-induced gene 3 and other interleukin-12-related molecules by human intestinal epithelium.
    Immunology. 2004 Jul;112(3):437-45.
    PMID: 15196212
  • Maaser C, Housley MP, Iimura M, Smith JR, Vallance BA, Finlay BB, Schreiber JR, Varki NM, Kagnoff MF, Eckmann L.
    Clearance of Citrobacter rodentium requires B cells but not secretory immunoglobulin A (IgA) or IgM antibodies.
    Infect Immun. 2004 Jun;72(6):3315-24.
    PMID: 15155635
  • Egan LJ, Eckmann L, Greten FR, Chae S, Li ZW, Myhre GM, Robine S, Karin M, Kagnoff MF.
    IkappaB-kinasebeta-dependent NF-kappaB activation provides radioprotection to the intestinal epithelium.
    Proc Natl Acad Sci U S A. 2004 Feb 24;101(8):2452-7.
    PMID: 14983030
  • Kim JG, Lee SJ, Kagnoff MF.
    Nod1 is an essential signal transducer in intestinal epithelial cells infected with bacteria that avoid recognition by toll-like receptors.
    Infect Immun. 2004 Mar;72(3):1487-95.
    PMID: 14977954
  • Egan LJ, Eckmann L, Greten FR, Chae S, Li ZW, Myhre GM, Robine S, Karin M, Kagnoff MF.
    I{kappa}B-kinase{beta}-dependent NF-{kappa}B activation provides radioprotection to the intestinal epithelium.
    Proc Natl Acad Sci U S A. 2004 Feb 11 [Epub ahead of print]
    PMID: 14960732
  • Hase K, Murakami M, Iimura M, Cole SP, Horibe Y, Ohtake T, Obonyo M, Gallo RL, Eckmann L, Kagnoff MF.
    Expression of LL-37 by human gastric epithelial cells as a potential host defense mechanism against Helicobacter pylori.
    Gastroenterology. 2003 Dec;125(6):1613-25.
    PMID: 14724813
  • Dwinell MB, Ogawa H, Barrett KE, Kagnoff MF.
    Stromal cell-derived factor-1/CXCL12 regulates cyclic AMP production and ion transport in intestinal epithelial cells via CXCR4.
    Am J Physiol Gastrointest Liver Physiol. 2003 Dec 18 [Epub ahead of print]
    PMID: 14684377
  • Egan LJ, De Lecea A, Lehrman ED, Myhre GM, Eckmann L, Kagnoff MF.
    Nuclear Factor {kappa}B Activation Promotes Restitution of Wounded Intestinal Epithelial Monolayers.
    Am J Physiol Cell Physiol.
    PMID: 12826601
  • Chen LW, Egan L, Li ZW, Greten FR, Kagnoff MF, Karin M.
    The two faces of IKK and NF-kappaB inhibition: prevention of systemic inflammation but increased local injury following intestinal ischemia-reperfusion.
    Nat Med. 2003 May;9(5):575-81.
    PMID: 12692538
  • Paesold G, Guiney DG, Eckmann L, Kagnoff MF.
    Genes in the Salmonella pathogenicity island 2 and the Salmonella virulence plasmid are essential for Salmonella-induced apoptosis in intestinal epithelial cells.
    Cell Microbiol. 2002 Nov;4(11):771-81.
    PMID: 12427099
  • Berin MC, Darfeuille-Michaud A, Egan LJ, Miyamoto Y, Kagnoff MF.
    Role of EHEC O157:H7 virulence factors in the activation of intestinal epithelial cell NF-kappaB and MAP kinase pathways and the upregulated expression of interleukin 8.
    Cell Microbiol. 2002 Oct;4(10):635-48.
    PMID: 12366401
  • Kagnoff MF.
    Celiac disease pathogenesis: the plot thickens.
    Gastroenterology. 2002 Sep;123(3):939-43. Review. No abstract available.
    PMID: 12198718
  • Maaser C, Kagnoff MF.
    Role of the intestinal epithelium in orchestrating innate and adaptive mucosal immunity.
    Z Gastroenterol. 2002 Jul;40(7):525-9.
    PMID: 12122602
  • Maaser C, Eckmann L, Paesold G, Kim HS, Kagnoff MF.
    Ubiquitous production of macrophage migration inhibitory factor by human gastric and intestinal epithelium.
    Gastroenterology. 2002 Mar;122(3):667-80.
    PMID: 11875000
  • Hase K, Eckmann L, Leopard JD, Varki N, Kagnoff MF.
    Cell Differentiation Is a Key Determinant of Cathelicidin LL-37/Human Cationic Antimicrobial Protein 18 Expression by Human Colon Epithelium.
    Infect Immun. 2002 Feb;70(2):953-63.
    PMID: 11796631
  • Langford TD, Housley MP, Boes M, Chen J, Kagnoff MF, Gillin FD, Eckmann L.
    Central importance of immunoglobulin A in host defense against Giardia spp.
    Infect Immun. 2002 Jan;70(1):11-8.
    PMID: 11748158
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  • Eckmann L, Kagnoff MF. Cytokines in host defense against Salmonella.
    Microbes Infect. 2001 Nov;3(14-15):1191-200.
    PMID: 11755407
  • Kagnoff MF, Eckmann L. Analysis of host responses to microbial infection using gene expression profiling.
    Curr Opin Microbiol. 2001 Jun;4(3):246-50. Review.
    PMID: 11378474
  • Berin MC, Dwinell MB, Eckmann L, Kagnoff MF.
    Production of MDC/CCL22 by human intestinal epithelial cells.
    Am J Physiol Gastrointest Liver Physiol. 2001 Jun;280(6):G1217-26.
    PMID: 11352815
  • Berin MC, Eckmann L, Broide DH, Kagnoff MF. Regulated production of the T helper 2-type T-cell chemoattractant TARC by human bronchial epithelial cells in vitro and in human lung xenografts.
    Am J Respir Cell Mol Biol. 2001 Apr;24(4):382-9.
    PMID: 11306430
  • Izadpanah A, Dwinell MB, Eckmann L, Varki NM, Kagnoff MF.
    Regulated MIP-3alpha/CCL20 production by human intestinal epithelium: mechanism for modulating mucosal immunity.
    Am J Physiol Gastrointest Liver Physiol. 2001 Apr;280(4):G710-9.
    PMID: 11254498
  • Dwinell, M.B., Lugering, N., Eckmann, L., and Kagnoff, M.F. Regulated production of interferon-inducible T-cell chemoattractants by human intestinal epithelial cells.
    Gastroenterology. 2001 Jan;120(1):49-59.
    PMID: 11208713
  • O'Neil, D.A., Cole, S.P., Martin-Porter, E., Liu, L., Ganz, T., and Kagnoff,M.F. Regulation of human beta-defensins by gastric epithelial cells in response to infection with Helicobacter pylori or stimulation with interleukin-1. Infect Immun. 2000 Sep;68(9):5412-5. PMID: 10948173
  • Eckmann L, Smith JR, Housley MP, Dwinell MB, Kagnoff MF.
    Analysis by high density cDNA arrays of altered gene expression in human intestinal epithelial cells in response to infection with
    the invasive enteric bacteria Salmonella.
    J Biol Chem. 2000 May 12;275(19):14084-94.
    PMID: 10799483; UI: 20261525
  • McCole DF, Eckmann L, Laurent F, Kagnoff MF.
    Intestinal epithelial cell apoptosis following Cryptosporidium parvum infection.
    Infect Immun. 2000 Mar;68(3):1710-3.
    PMID: 10678994; UI: 20143793
  • Eckmann L, Laurent F, Langford TD, Hetsko ML, Smith JR, Kagnoff MF, Gillin FD.
    Nitric oxide production by human intestinal epithelial cells and competition for arginine as potential determinants of host defense against the lumen-dwelling pathogen Giardia lamblia.
    J Immunol. 2000 Feb 1;164(3):1478-87.
    PMID: 10640765; UI: 20109103
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  • Laurent F, McCole D, Eckmann L, Kagnoff MF.
    Pathogenesis of Cryptosporidium parvum infection.
    Microbes Infect. 1999 Feb;1(2):141-148.
    PMID: 10594978
  • O'Neil DA, Porter EM, Elewaut D, Anderson GM, Eckmann L, Ganz T, Kagnoff MF.
    Expression and regulation of the human beta-defensins hBD-1 and hBD-2 in intestinal epithelium.
    J Immunol. 1999 Dec 15;163(12):6718-24.
    PMID: 10586069; UI: 20054559
  • Merendino N, et al.
    Human intestinal epithelial cells express receptors for platelet-activating factor.
    Am J Physiol. 1999 Oct;277(4 Pt 1):G810-G818.
    PMID: 10516147.
  • Dwinell MB, et al.
    Chemokine receptor expression by human intestinal epithelial cells.
    Gastroenterology. 1999 Aug;117(2):359-67.
    PMID: 10419917; UI: 99350297.
  • Elewaut D, et al.
    NF-kappa B is a central regulator of the intestinal epithelial cell innate immune response induced by infection with enteroinvasive bacteria.
    J Immunol. 1999 Aug 1;163(3):1457-66.
    PMID: 10415047; UI: 99343757.
  • Clot F, et al.
    HLA-DR53 molecules are associated with susceptibility to celiac disease and selectively bind gliadin-derived peptides.
    Immunogenetics. 1999 Aug;49(9):800-7.
    PMID: 10398807; UI: 99328907.
  • Kagnoff MF.
    Thoughts of the editor at midterm.
    Am J Physiol. 1999 Jun;276(6 Pt 1):G1311-2. No abstract available.
    PMID: 10362632.
  • Kagnoff MF, et al.
    [See Related Articles]
    Human immunodeficiency virus type 1 (HIV-1) infection and expression in intestinal epithelial cells: role of protein kinase A and C pathways
    in HIV-1 transcription.
    J Infect Dis. 1999 May;179 Suppl 3:S444-7. Review.
    PMID: 10099116; UI: 99201455.
  • Lowe DC, et al.
    Characterization of candidate live oral Salmonella typhi vaccine strains harboring defined mutations in aroA, aroC, and htrA.
    Infect Immun. 1999 Feb;67(2):700-7.
    PMID: 9916080; UI: 99115546.
  • Kim JM, et al. Apoptosis of human intestinal epithelial cells after bacterial invasion.
    J Clin Invest. 1998 Nov 15;102(10):1815-23.
    [MEDLINE record in process]
    PMID: 9819367; UI: 99038185.
  • Witthoft T, et al.
    Enteroinvasive bacteria directly activate expression of iNOS and NO production in human colon epithelial cells.
    Am J Physiol. 1998 Sep;275(3 Pt 1):G564-71.
    PMID: 9724270; UI: 98400913.
  • Kim PH, et al.
    Cholera toxin and cholera toxin B subunit induce IgA switching through the action of TGF-beta 1.
    J Immunol. 1998 Feb 1;160(3):1198-203.
    PMID: 9570534; UI: 98230461.
  • Kagnoff MF.
    Current concepts in mucosal immunity. III. Ontogeny and function of gamma delta T cells in the intestine.
    Am J Physiol. 1998 Mar;274(3 Pt 1):G455-8. Review.
    PMID: 9530144; UI: 98191175.
  • Laurent F, et al.
    Human intestinal epithelial cells respond to Cryptosporidium parvum infection with increased prostaglandin H synthase 2
    expression and prostaglandin E2 and F2alpha production.
    Infect Immun. 1998 Apr;66(4):1787-90.
    PMID: 9529115; UI: 98187964.
  • Eckmann L, et al.
    D-myo-Inositol 1,4,5,6-tetrakisphosphate produced in human intestinal epithelial cells in response to Salmonella invasion inhibits
    phosphoinositide 3-kinase signaling pathways.
    Proc Natl Acad Sci U S A. 1997 Dec 23; 94(26): 14456-14460.
    PMID: 9405634; UI: 98070773.
  • Laurent F, et al.
    Cryptosporidium parvum infection of human intestinal epithelial cells induces the polarized secretion of C-X-C chemokines.
    Infect Immun. 1997 Dec; 65(12): 5067-5073.
    PMID: 9393797; UI: 98053946.
  • Yang SK, et al.
    Differential and regulated expression of C-X-C, C-C, and C-chemokines by human colon epithelial cells.
    Gastroenterology. 1997 Oct; 113(4): 1214-1223.
    PMID: 9322516; UI: 97463815.
  • Rowell DL, et al.
    Human hepatocytes express an array of proinflammatory cytokines after agonist stimulation or bacterial invasion.
    Am J Physiol. 1997 Aug; 273(2 Pt 1): G322-G332.
    PMID: 9277410; UI: 97423468.
  • Eckmann L, et al.
    Role of intestinal epithelial cells in the host secretory response to infection by invasive bacteria. Bacterial entry induces epithelial
    prostaglandin h synthase-2 expression and prostaglandin E2 and F2alpha production.
    J Clin Invest. 1997 Jul 15; 100(2): 296-309.
    PMID: 9218506; UI: 97364796.
  • Kagnoff MF, et al.
    Epithelial cells as sensors for microbial infection.
    J Clin Invest. 1997 Jul 1; 100(1): 6-10. Review. No abstract available.
    PMID: 9202050; UI: 97347411.
  • Rabbi MF, et al.
    U5 region of the human immunodeficiency virus type 1 long terminal repeat contains TRE-like cAMP-responsive elements that
    bind both AP-1 and CREB/ATF proteins.
    Virology. 1997 Jun 23; 233(1): 235-245.
    PMID: 9201233; UI: 97344866.
  • Holtmeier W, et al.
    The TCR-delta repertoire in human intestine undergoes characteristic changes during fetal to adult development.
    J Immunol. 1997 Jun 15; 158(12): 5632-5641.
    PMID: 9190911; UI: 97334214.
  • Varki AP, et al.
    Passing the baton at high speed: time to hand over to a new editorial board.
    J Clin Invest. 1997 Feb 15; 99(4): 553-554. No abstract available.
    PMID: 9045851; UI: 97197555.
  • Roebuck KA, et al.
    HIV-1 Tat protein can transactivate a heterologous TATAA element independent of viral promoter sequences and the
    trans-activation response element.
    AIDS. 1997 Feb; 11(2): 139-146.
    PMID: 9030359; UI: 97182319.
  • Cole SP, et al.
    Coccoid and spiral Helicobacter pylori differ in their abilities to adhere to gastric epithelial cells and induce interleukin-8
    Infect Immun. 1997 Feb; 65(2): 843-846.
    PMID: 9009355; UI: 97162368.
  • Guiney DG, et al.
    Host/pathogen interactions: series introduction.
    J Clin Invest. 1997 Jan 15; 99(2): 155. No abstract available.
    PMID: 9005980; UI: 97158620.
  • Rasmussen SJ, et al.
    Secretion of proinflammatory cytokines by epithelial cells in response to Chlamydia infection suggests a central role for epithelial
    cells in chlamydial pathogenesis.
    J Clin Invest. 1997 Jan 1; 99(1): 77-87.
    PMID: 9011579; UI: 97148774.
  • Holtmeier W, et al.
    Distinct delta T cell receptor repertoires in monozygotic twins concordant for coeliac disease.
    Clin Exp Immunol. 1997 Jan; 107(1): 148-157.
    PMID: 9010270; UI: 97163450.
  • Chowers Y, et al.
    Increased proinflammatory cytokine gene expression in the colonic mucosa of coeliac disease patients in the early period after
    gluten challenge.
    Clin Exp Immunol. 1997 Jan; 107(1): 141-147.
    PMID: 9010269; UI: 97163449.
  • Morzycka-Wroblewska E, et al.
    Differential expression of HLA-DQA1 alleles associated with promoter polymorphism.
    Immunogenetics. 1997; 45(3): 163-170.
    PMID: 8995182; UI: 97152404.
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  • Chen CY, et al.
    Expression of Salmonella typhimurium rpoS and rpoS-dependent genes in the intracellular environment of eukaryotic cells.
    Infect Immun. 1996 Nov; 64(11): 4739-4743.
    PMID: 8890234; UI: 97045169.
  • Huang GT, et al.
    Infection of human intestinal epithelial cells with invasive bacteria upregulates apical intercellular adhesion molecule-1 (ICAM)-1)
    expression and neutrophil adhesion.
    J Clin Invest. 1996 Jul 15; 98(2): 572-583.
    PMID: 8755670; UI: 96331265.
  • Roebuck KA, et al.
    Activating protein-1 cooperates with phorbol ester activation signals to increase HIV-1 expression.
    AIDS. 1996 Jul; 10(8): 819-826.
    PMID: 8828738; UI: 96426444.
  • Eckmann L, et al.
    Genetically resistant (Ityr) and susceptible (Itys) congenic mouse strains show similar cytokine responses following infection
    with Salmonella dublin.
    J Immunol. 1996 Apr 15; 156(8): 2894-2900.
    PMID: 8609409; UI: 96183244.
  • Kagnoff MF.
    Mucosal immunology: new frontiers.
    Immunol Today. 1996 Feb; 17(2): 57-59.
    PMID: 8808050; UI: 96403772.
  • Kagnoff MF.
    Oral tolerance: mechanisms and possible role in inflammatory joint diseases.
    Baillieres Clin Rheumatol. 1996 Feb; 10(1): 41-54. Review.
    PMID: 8674148; UI: 96259573.
  • Eckmann L, et al.
    Entamoeba histolytica trophozoites induce an inflammatory cytokine response by cultured human cells through the paracrine action of cytolytically released
    interleukin-1 alpha.
    J Clin Invest. 1995 Sep; 96(3): 1269-1279.
    PMID: 7657801; UI: 95386681.
  • Holtmeier W, et al.
    The delta T cell receptor repertoire in human colon and peripheral blood is oligoclonal irrespective of V region usage.
    J Clin Invest. 1995 Aug; 96(2): 1108-1117.
    PMID: 7635946; UI: 95362812.
  • Eckmann L, et al.
    Intestinal epithelial cells as watchdogs for the natural immune system.
    Trends Microbiol. 1995 Mar; 3(3): 118-120.
    PMID: 7773590; UI: 95291654.
  • Chowers Y, et al.
    Inverse PCR amplification of rare T cell receptor delta messages from mucosal biopsy specimens.
    J Immunol Methods. 1995 Feb 27; 179(2): 261-263.
    PMID: 7876573; UI: 95181830.
  • Jung HC, et al.
    A distinct array of proinflammatory cytokines is expressed in human colon epithelial cells in response to bacterial invasion.
    J Clin Invest. 1995 Jan; 95(1): 55-65.
    PMID: 7814646; UI: 95114144.
  • Eckmann L, et al.
    Increased transcription and coordinate stabilization of mRNAs for secreted immunoglobulin alpha heavy chain and kappa light chain following stimulation of
    immunoglobulin A expressing B cells.
    J Biol Chem. 1994 Dec 30; 269(52): 33102-33108.
    PMID: 7806538; UI: 95105200.
  • Eckmann L, et al.
    Colonic epithelial cell lines as a source of interleukin-8: stimulation by inflammatory cytokines and bacterial lipopolysaccharide.
    Immunology. 1994 Aug; 82(4): 505. No abstract available.
    PMID: 7835910; UI: 95137607.
  • Kagnoff MF. A question of balance: ups and downs of mucosal inflammation.
    J Clin Invest. 1994 Jul; 94(1): 1. No abstract available.
    PMID: 8040251; UI: 94314882.
  • Chowers Y, et al. The V delta 1 T cell receptor repertoire in human small intestine and colon.
    J Exp Med. 1994 Jul 1; 180(1): 183-190.
    PMID: 8006582; UI: 94275371.
  • Franco A, et al.
    Peripheral T cell response to A-gliadin in celiac disease: differential processing and presentation capacities of Epstein-Barr-transformed B cells and fibroblasts.
    Clin Immunol Immunopathol. 1994 Apr; 71(1): 75-81.
    PMID: 7511085; UI: 94185342.
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  • Eckmann L, et al.
    Differential cytokine expression by human intestinal epithelial cell lines: regulated expression of interleukin 8.
    Gastroenterology. 1993 Dec; 105(6): 1689-1697.
    PMID: 8253345; UI: 94074849.
  • Eckmann L, et al.
    Epithelial cells secrete the chemokine interleukin-8 in response to bacterial entry.
    Infect Immun. 1993 Nov; 61(11): 4569-4574.
    PMID: 8406853; UI: 94011363
  • Kagnoff MF.
    Immunology of the intestinal tract.
    Gastroenterology. 1993 Nov; 105(5): 1275-1280. Review.
    PMID: 8224631; UI: 94040477.
  • Roebuck KA, et al.
    Identification of c-fos-responsive elements downstream of TAR in the long terminal repeat of human immunodeficiency virus type-1.
    J Clin Invest. 1993 Sep; 92(3): 1336-1348.
    PMID: 8376588; UI: 93388866.
  • Morzycka-Wroblewska E, et al.
    Structure and evolution of the promoter regions of the DQA genes.
    Immunogenetics. 1993; 37(5): 364-372.
    PMID: 8428769; UI: 93154778.
  • Eckmann L, et al.
    Cytokine-induced differentiation of IgA B cells: studies using an IgA expressing B-cell lymphoma.
    Immunology. 1992 Jun; 76(2): 235-241.
    PMID: 1634247; UI: 92340109.
  • Kagnoff MF.
    Celiac disease. A gastrointestinal disease with
    environmental, genetic, and immunologic components.
    Gastroenterol Clin North Am. 1992 Jun; 21(2): 405-425.
    PMID: 1512049; UI: 92380750.
  • Omary MB, et al.
    Biochemical and morphological differentiation of the
    human colonic epithelial cell line SW620 in the presence
    of dimethylsulfoxide.
    J Cell Biochem. 1992 Mar; 48(3): 316-323.
    PMID: 1400616; UI: 93016307.
  • Omary MB, et al.
    A tyrosine sulfated human glycoprotein with an unusual
    cell distribution.
    Mol Immunol. 1992 Jan; 29(1): 9-19.
    PMID: 1731194; UI: 92114895.
  • Fronek Z, et al.
    Molecular analysis of HLA DP and DQ genes associated
    with dermatitis herpetiformis.
    J Invest Dermatol. 1991 Nov; 97(5): 799-802.
    PMID: 1919044; UI: 92013229.
  • Omary MB, et al.
    HIV-1 infection and expression in human colonic cells:
    infection and expression in CD4+ and CD4- cell lines.
    AIDS. 1991 Mar; 5(3): 275-281.
    PMID: 2059367; UI: 91283036.
  • Schoenbeck S, et al.
    Detection of individual Peyer's patch T cells that
    produce interleukin-5 and interferon-gamma.
    J Immunol Methods. 1991 Mar 1; 137(1): 47-54.
    PMID: 1826301; UI: 91185843.
  • Kagnoff MF, et al. Expression of human immunodeficiency virus-1 in
    human colonic cells.
    Immunol Res. 1991; 10(3-4): 452-455. No abstract
    PMID: 1955772; UI: 92065088.
  • Kagnoff MF, et al.
    Effects of transforming growth factor beta-1 and
    interleukin-5 on IgA isotype switching at the clonal level.
    Immunol Res. 1991; 10(3-4): 396-399. No abstract
    PMID: 1955764; UI: 92065076.
  • Kagnoff MF, et al.
    Detection by immunofluorescence of
    lymphokine-producing T cells.
    Immunol Res. 1991; 10(3-4): 255-257. No abstract
    PMID: 1955750; UI: 92065049.
  • Kim PH, et al.
    Transforming growth factor beta 1 increases IgA
    isotype switching at the clonal level.
    J Immunol. 1990 Dec 1; 145(11): 3773-3778.
    PMID: 2246513; UI: 91060959.
  • Kim PH, et al.
    Transforming growth factor-beta 1 is a costimulator for
    IgA production.
    J Immunol. 1990 May 1; 144(9): 3411-3416.
    PMID: 2329276; UI: 90229728.
  • Kagnoff MF.
    Understanding the molecular basis of coeliac disease.
    Gut. 1990 May; 31(5): 497-499. Review. No abstract available.
    PMID: 2112501; UI: 90276888.
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  • Volk BA, et al.
    Analysis of RNA transcripts for HLA class II genes in
    human small intestinal biopsies.
    Gut. 1989 Sep; 30(9): 1220-1224.
    PMID: 2478425; UI: 90034336.
  • Kagnoff MF, et al.
    Structural analysis of the HLA-DR, -DQ, and -DP alleles
    on the celiac disease-associated HLA-DR3 (DRw17) haplotype.
    Proc Natl Acad Sci U S A. 1989 Aug; 86(16):
    PMID: 2788285; UI: 89345646.
  • Schoenbeck S, et al. Interleukin 5 is a differentiation factor for IgA B cells.
    Eur J Immunol. 1989 Jun; 19(6): 965-969.
    PMID: 2787753; UI: 89325438.
  • Devery JM, et al. Anti-gliadin antibody specificity for gluten-derived peptides toxic to coeliac patients.
    Clin Exp Immunol. 1989 Jun; 76(3): 384-390.
    PMID: 2752594; UI: 89324409.
  • Kelleher D, et al.
    Development and characterisation of T lymphocyte lines
    from human small intestinal biopsies.
    Gut. 1989 Apr; 30(4): 460-467.
    PMID: 2785473; UI: 89232871.
  • Schoenbeck S, et al.
    Vicia villosa agglutinin separates freshly isolated Peyer's
    Patch T cells into interleukin 5- or interleukin 2-producing subsets.
    J Exp Med. 1989 Apr 1; 169(4): 1491-1496.
    PMID: 2784488; UI: 89176903.
  • Kagnoff MF.
    Immunopathogenesis of celiac disease.
    Immunol Invest. 1989 Jan; 18(1-4): 499-508. Review.
    PMID: 2659519; UI: 89277469.
  • Kagnoff MF. Celiac disease: adenovirus and alpha gliadin.
    Curr Top Microbiol Immunol. 1989; 145: 67-78.
    Review. No abstract available.
    PMID: 2553337; UI: 90031715.
  • Omary MB, et al. An 80 to 85 kilodalton human phosphoglycoprotein associated with cell activation.
    J Immunol. 1988 Nov 15; 141(10): 3492-3497.
    PMID: 3183379; UI: 89035471.
  • Kelleher D, et al.
    Phorbol myristate acetate induces IL-2 secretion by HUT 78 cells by a mechanism independent of protein kinase C translocation.
    Immunology. 1988 Nov; 65(3): 351-355.
    PMID: 3264806; UI: 89092400.
  • Rodgers VD, et al.
    Abnormalities of the intestinal immune system in AIDS.
    Gastroenterol Clin North Am. 1988 Sep; 17(3): 487-494. Review.
    PMID: 3049357; UI: 89007057.
  • Wasserman SI, et al.
    Immune-related intestinal Cl- secretion. I. Effect of histamine on the T84 cell line.
    Am J Physiol. 1988 Jan; 254(1 Pt 1): C53-C62.
    PMID: 3337221; UI: 88104153.
  • Omary MB, et al.
    Structural heterogeneity of human Pgp-1 and its relationship with p85.
    Immunogenetics. 1988; 27(6): 460-464. No abstract available.
    PMID: 3286493; UI: 88226790.
  • Kagnoff MF.
    Oral tolerance.
    Monogr Allergy. 1988; 24: 222-226. Review. No abstract available.
    PMID: 3283530; UI: 88201935.
  • Howell MD, et al.
    An extended HLA-D region haplotype associated with celiac disease.
    Proc Natl Acad Sci U S A. 1988 Jan; 85(1): 222-226.
    PMID: 2893373; UI: 88124796.
  • Omary MB, et al.
    Identification of nuclear receptors for VIP on a human colonic adenocarcinoma cell line.
    Science. 1987 Dec 11; 238(4833): 1578-1581.
    PMID: 2825352; UI: 88070624.
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    Interleukin 5 and interleukin 4 produced by Peyer's patch T cells selectively enhance immunoglobulin A expression.
    J Immunol. 1987 Oct 15; 139(8): 2669-2674.
    PMID: 3498768; UI: 88009143.
  • Kagnoff MF, et al.
    Evidence for the role of a human intestinal adenovirus in the pathogenesis of coeliac disease.
    Gut. 1987 Aug; 28(8): 995-1001.
    PMID: 2822550; UI: 88030856.
  • Kaiserlian D, et al. Production of murine leukemia virus in the immunodeficient wasted mutant mouse is associated with the wst allele.
    Immunol Lett. 1987 Aug; 15(4): 277-283.
    PMID: 2447014; UI: 88085279.
  • Targan SR, et al.
    Immunologic mechanisms in intestinal diseases.
    Ann Intern Med. 1987 Jun; 106(6): 853-870. Review.
    PMID: 3555203; UI: 87211479.
  • Murray PD, et al.
    Regulation of the anti-alpha (1,3) dextran response: two populations of dextran-reactive B cells that differ in their T cell requirements for induction to antibody synthesis.
    J Immunol. 1987 Apr 15; 138(8): 2439-2444.
    PMID: 2435799; UI: 87167605.
  • Rodgers VD, et al.
    Gastrointestinal manifestations of the acquired immunodeficiency syndrome.
    West J Med. 1987 Jan; 146(1): 57-67. No abstract available.
    PMID: 3825111; UI: 87151464.
  • Howell MD, et al. Rapid identification of hybridization probes for chromosomal walking.
    Gene. 1987; 55(1): 41-45.
    PMID: 3040531; UI: 87305590.
  • Kagnoff MF, et al. T dependent induction of an IgA and IgM anti-polysaccharide response.
    Adv Exp Med Biol. 1987; 216A: 155-167. No abstract available.
    PMID: 2446467; UI: 88073328.
  • Klein JR, et al.
    Spontaneous in vitro evolution of lytic specificity of cytotoxic T lymphocyte clones isolated from murine intestinal epithelium.
    J Immunol. 1987 Jan 1; 138(1): 58-62.
    PMID: 2431060; UI: 87059058.
  • Elson CO, et al. Intestinal immunity and inflammation: recent progress.
    Gastroenterology. 1986 Sep; 91(3): 746-768. Review.
    PMID: 3089867; UI: 86275912.
  • Howell MD, et al.
    An HLA-D region restriction fragment length polymorphism associated with celiac disease.
    J Exp Med. 1986 Jul 1; 164(1): 333-338.
    PMID: 3014038; UI: 86253066.
  • Rodgers VD, et al.
    Abnormalities in intestinal mucosal T cells in **** populations including those with the lymphadenopathy syndrome and acquired immunodeficiency syndrome.
    Gastroenterology. 1986 Mar; 90(3): 552-558.
    PMID: 2935443; UI: 86109341.
  • Murray PD, et al.
    Regulation of the IgM and IgA anti-dextran B1355S response: synergy between IFN-gamma, BCGF II, and IL 2.
    J Immunol. 1985 Dec; 135(6): 4015-4020.
    PMID: 2415594; UI: 86060882.
  • Klein JR, et al. A murine cytotoxic T lymphocyte clone from the intestinal mucosa that is antigen specific for proliferation and displays broadly reactive inducible cytotoxic activity.
    J Immunol. 1985 Dec; 135(6): 3697-3703.
    PMID: 2415582; UI: 86060835.
  • Murray PD, et al.
    Differential effect of interferon-gamma and interleukin-2 on the induction of IgA and IgM anti-dextran responses.
    Cell Immunol. 1985 Oct 15; 95(2): 437-442.
    PMID: 2412709; UI: 86002362.
  • Levenson SD, et al.
    Specificity of antigliadin antibody in celiac disease.
    Gastroenterology. 1985 Jul; 89(1): 1-5.
    PMID: 4007398; UI: 85231840.
  • Kagnoff MF.
    Coeliac disease: genetic, immunological and environmental factors in disease pathogenesis.
    Scand J Gastroenterol Suppl. 1985; 114: 45-54. Review.
    PMID: 3937222; UI: 86122637.
  • Cole SG, et al.
    Celiac disease.
    Annu Rev Nutr. 1985; 5: 241-266. Review. No abstract available.
    PMID: 3896269; UI: 85280095.
  • Klein JR, et al.
    Nonspecific recruitment of cytotoxic effector cells in the intestinal mucosa of antigen-primed mice.
    J Exp Med. 1984 Dec 1; 160(6): 1931-1936.
    PMID: 6334717; UI: 85081917.
  • Kagnoff MF, et al. Possible role for a human adenovirus in the pathogenesis of celiac disease.
    J Exp Med. 1984 Nov 1; 160(5): 1544-1557.
    PMID: 6491604; UI: 85032526.
  • Austin RK, et al.
    Sensitive radioimmunoassay for the broad-spectrum antiviral agent ribavirin.
    Antimicrob Agents Chemother. 1983 Nov; 24(5): 696-701.
    PMID: 6660848; UI: 84103099.
  • Kagnoff MF, et al.
    Association between Crohn's disease and immunoglobulin heavy chain (Gm) allotypes.
    Gastroenterology. 1983 Nov; 85(5): 1044-1047.
    PMID: 6578156; UI: 84005658.
  • Kagnoff MF, et al. Lymphokine-mediated activation of a T cell-dependent IgA antipolysaccharide response.
    J Immunol. 1983 Nov; 131(5): 2210-2214.
    PMID: 6195258; UI: 84034184.
  • Weiss JB, et al.
    Gluten-sensitive enteropathy. Immunoglobulin G heavy-chain (Gm) allotypes and the immune response to wheat gliadin.
    J Clin Invest. 1983 Jul; 72(1): 96-101.
    PMID: 6409931; UI: 83266204.
  • Kagnoff MF.
    Humoral antibody responses to the bacterial polysaccharide dextran B1355.
    Ann N Y Acad Sci. 1983 Jun 30; 409: 114-128. No abstract available.
    PMID: 6191609; UI: 83254405.
  • Kagnoff MF, et al. Immunoglobulin allotype markers in gluten-sensitive enteropathy.
    Lancet. 1983 Apr 30; 1(8331): 952-953.
    PMID: 6132268; UI: 83166121.
  • Rivier DA, et al. Age-dependence of the IgA anti-alpha (1 leads to 3) dextran B1355 response in vitro.
    Scand J Immunol. 1983 Feb; 17(2): 115-121.
    PMID: 6188201; UI: 83171209.
  • Kagnoff MF, et al.
    Celiac sprue: correlation with murine T cell responses to wheat gliadin components.
    J Immunol. 1982 Dec; 129(6): 2693-2697.
    PMID: 6183341; UI: 83058046.
  • Kagnoff MF.
    Two genetic loci control the murine immune response to A-gliadin, a wheat protein that activates coeliac sprue.
    Nature. 1982 Mar 11; 296(5853): 158-160. No abstract available.
    PMID: 6801524; UI: 82148588.
  • Kagnoff MF.
    Oral tolerance.
    Ann N Y Acad Sci. 1982; 392: 248-265. No abstract available.
    PMID: 6182827; UI: 83046691.
  • Trefts PE, et al. T cell-dependent IgA anti-polysaccharide response in vitro.
    Nature. 1981 Jul 9; 292(5819): 163-164. No abstract available.
    PMID: 6165897; UI: 81220993.
  • Trefts PE, et al.
    Gluten-sensitive enteropathy. I. The T-dependent anti-A-gliadin antibody response maps to the murine major histocompatibility
    J Immunol. 1981 Jun; 126(6): 2249-2252.
    PMID: 6971892; UI: 81193082.
  • Kagnoff MF.
    Effects of antigen-feeding on intestinal and systemic immune responses. IV. Similarity between the suppressor factor in mice after
    erythrocyte-lysate injection and erythrocyte feeding.
    Gastroenterology. 1980 Jul; 79(1): 54-61.
    PMID: 7380224; UI: 80202488.

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  • Kagnoff MF.
    IgA anti-dextran B1355 responses.
    J Immunol. 1979 Mar; 122(3): 866-870.
    PMID: 109506; UI: 79195151.
  • Hahn WV, et al.
    Immune responses in human colon cancer. I. Microcytotoxicity assay for measuring killing of adherent human colon cancer cell lines.
    Gastroenterology. 1978 Nov; 75(5): 800-805.
    PMID: 700323; UI: 79025447.
  • Kagnoff MF.
    Effects of antigen-feeding on intestinal and systemic immune responses. III. Antigen-specific serum-mediated suppression of
    humoral antibody responses after antigen feeding.
    Cell Immunol. 1978 Sep 15; 40(1): 186-203. No abstract available.
    PMID: 81111; UI: 79023150.
  • Kagnoff MF.
    On the etiology of Crohn's disease.
    Gastroenterology. 1978 Sep; 75(3): 526-527. No abstract available.
    PMID: 680518; UI: 78239925.
  • Kagnoff MF. Effects of antigen-feeding on intestinal and systemic immune responses. II. Suppression of delayed-type hypersensitivity
    J Immunol. 1978 May; 120(5): 1509-1513. No abstract available.
    PMID: 659859; UI: 78195337.
  • Hahn WV, et al.
    Immune responses in human colon cancer. II. Cytotoxic antibody detected in patients' sera.
    J Natl Cancer Inst. 1978 Apr; 60(4): 779-784.
    PMID: 75979; UI: 78133009.
  • Kagnoff MF.
    Effects of antigen-feeding on intestinal and systemic immune responses. I. priming of precursor cytotoxic T cells by antigen feeding.
    J Immunol. 1978 Feb; 120(2): 395-399.
    PMID: 304457; UI: 78088327.
  • Kagnoff MF.
    Functional characteristics of Peyer's patch lymphoid cells. IV. Effect of antigen feeding on the frequency of antigen-specific B cells.
    J Immunol. 1977 Mar; 118(3): 992-997.
    PMID: 300396; UI: 77142561.
  • Kagnoff MF, et al. Antibody-dependent cell-mediated cytotoxicity. Comparative ability of murine Peyer's patch and spleen cells to lyse lipopolysaccharide-coated and uncoated erythrocytes.
    Gastroenterology. 1976 Mar; 70(3): 341-346.
    PMID: 1082425; UI: 76118535.
  • Kagnoff MF.
    Functional characteristics of intestinal Peyer's patch lymphoid cells.
    Ann N Y Acad Sci. 1976; 278: 539-545. No abstract available.
    PMID: 1085594; UI: 76276318.
  • Kagnoff MF.
    Functional characteristics of Peyer's patch cells. III. Carrier priming of T cells by antigen feeding.
    J Exp Med. 1975 Dec 1; 142(6): 1425-1435.
    PMID: 1081580; UI: 76070750.
  • Campbell SM, et al.
    Demonstration of organ differences in peripheral B cell populations through the use of deficient fetal bovine serum.
    J Immunol. 1975 Mar; 114(3): 992-996.
    PMID: 803537; UI: 75096250.
  • Kagnoff MF.
    Induction and paralysis: a conceptual framework from which to examine the intestinal immune system.
    Gastroenterology. 1974 Jun; 66(6): 1240-1256. Review. No abstract available.
    PMID: 4597753; UI: 74166399.
  • Kagnoff MF, et al.
    Functional characteristics of Peyer's patch lymphoid cells. II. Lipopolysaccharide is thymus dependent.
    J Exp Med. 1974 Feb 1; 139(2): 407-413. No abstract available.
    PMID: 4589992; UI: 74086228.
  • Kagnoff MF, et al.
    Functional characteristics of Peyer's patch lymphoid cells. I. Induction of humoral antibody and cell-mediated allograft reactions.
    J Exp Med. 1974 Feb 1; 139(2): 398-406. No abstract available.
    PMID: 4589991; UI: 74086227.
  • Kagnoff MF, et al.
    In vitro kinetics of intestinal secretory IgA secretion.
    J Immunol. 1973 Jan; 110(1): 297-300. No abstract available.
    PMID: 4685407; UI: 73091031.
  • Kagnoff MF, et al.
    Organ culture of rabbit small intestine: prolonged in vitro steady state protein synthesis and secretion and secretory IgA secretion.
    Gastroenterology. 1972 Oct; 63(4): 541-551. No abstract available.
    PMID: 4627771; UI: 73016560.
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